Colon Cancer
Expert Diagnosis & Surgical Treatment

4th

Most common UK cancer

90%+

Stage I 5-year survival

Keyhole

Minimally invasive surgery

MDT

Multidisciplinary team approach

— What is Colon Cancer?

Understanding Colon Cancer

Colon cancer (bowel cancer) is a malignant tumour arising from the lining of the large intestine (colon). It is the fourth most common cancer in the UK and the second most common cause of cancer death. However, when detected early, colon cancer is highly treatable, with surgery offering an excellent chance of cure in localised disease.

The majority of colon cancers develop from pre-cancerous polyps (adenomas) over a period of years, which is why colonoscopic surveillance and the NHS Bowel Cancer Screening Programme are so important. Identifying and removing polyps before they become cancerous prevents bowel cancer from developing at all.

Early Stage

Early and Localised Colon Cancer

Confined to the bowel wall or nearby lymph nodes. Surgery is the primary treatment and outcomes are excellent, over 90% 5-year survival for Stage I disease.

Advanced

Locally Advanced or Metastatic

Disease extending beyond the colon or involving distant organs (liver, lung). A multidisciplinary approach combining surgery, chemotherapy and targeted therapy offers the best outcomes.

— Warning Signs

Symptoms to Recognise

💩

Change in Bowel Habit

Persistent diarrhoea, constipation, or a change in stool consistency lasting more than three weeks, particularly in the absence of an obvious cause.

🔴

Rectal Bleeding

Blood mixed with stool or fresh rectal bleeding without an obvious benign cause warrants urgent investigation to exclude malignancy.

Abdominal Pain

Persistent or cramping lower abdominal pain, sometimes associated with bloating. Colic from bowel obstruction is a more urgent presentation.

Unexplained Weight Loss

Unintentional weight loss of more than 5% body weight over weeks to months is a red flag symptom requiring urgent assessment.

😴

Fatigue and Anaemia

Iron deficiency anaemia caused by occult (hidden) blood loss from a right-sided tumour, often presenting with fatigue before any obvious rectal bleeding.

🚫

Bowel Obstruction

Inability to open bowels, vomiting and abdominal distension may indicate advanced disease causing obstruction, a surgical emergency.

⚕ Clinical Note

Any of these symptoms, particularly in patients over 40 or with a family history of bowel cancer, warrant prompt specialist assessment. Do not delay seeking evaluation, early detection significantly improves outcomes.

— Diagnosis and Staging

Investigation Pathway

1

Colonoscopy and Biopsy

The definitive diagnostic investigation. The entire colon is examined and any suspicious lesion is biopsied to confirm the histological diagnosis.

2

CT Chest, Abdomen and Pelvis

Staging CT to assess local extent of the tumour and identify any spread to lymph nodes, liver, lungs or other organs.

3

MRI and PET-CT (Selected Cases)

MRI for local staging of complex tumours; PET-CT to characterise indeterminate lesions or assess response to pre-operative chemotherapy.

4

Multidisciplinary Team Review

All cases are discussed at the colorectal cancer MDT meeting, including oncology, radiology and pathology, to agree the optimal treatment plan.

— Treatment Options

Management Pathway

1

Laparoscopic / Robotic Colectomy

Minimally invasive surgery · Gold standard · Day 3–5 discharge
  • Right Hemicolectomy For cancers of the ascending colon and hepatic flexure. The right side of the colon and associated lymph nodes are removed. Laparoscopic or robotic approach.
  • Left Hemicolectomy / Sigmoid Colectomy For descending colon and sigmoid tumours. The affected segment and regional lymph nodes are resected with restoration of bowel continuity.
  • Robotic Advantages Mr Kumar routinely performs robotic colectomy, offering superior 3D visualisation and precision, particularly valuable in the pelvis and for technically demanding resections.
The majority of colon cancer resections are now performed laparoscopically or robotically, offering shorter hospital stay, less pain, and equivalent oncological outcomes to open surgery.
2

Adjuvant Chemotherapy

Post-operative treatment for higher-risk disease
  • Who Needs It? Stage III (node-positive) disease and selected high-risk Stage II tumours benefit from adjuvant chemotherapy to reduce the risk of recurrence.
  • CAPOX / FOLFOX Standard regimens combining capecitabine and oxaliplatin (CAPOX) or 5-fluorouracil, leucovorin and oxaliplatin (FOLFOX), typically given for 3 to 6 months after surgery.
  • Targeted Therapy EGFR inhibitors or bevacizumab may be added for RAS wild-type or BRAF-mutated tumours in advanced disease.
Chemotherapy decisions are made by the oncology team in conjunction with Mr Kumar at the MDT, based on pathological staging and molecular tumour characteristics.
3

Management of Metastatic Disease

For spread to liver or lung
  • Liver Resection Selected patients with liver-only metastases can be cured by surgical resection of liver deposits, often combined with chemotherapy.
  • Ablation Therapies Radiofrequency ablation or stereotactic radiotherapy for small or surgically inaccessible liver or lung metastases.
  • Palliative Chemotherapy For unresectable metastatic disease, chemotherapy aims to control the cancer, relieve symptoms and prolong survival.
Metastatic colon cancer is not always incurable. A significant proportion of patients with liver or lung metastases can undergo curative-intent resection with excellent long-term outcomes.

— Follow-Up and Surveillance

After Treatment

After curative surgery, regular follow-up is essential to detect recurrence early. Mr Kumar provides structured post-operative surveillance including:

🔬

CEA Blood Tests

Carcinoembryonic antigen (CEA) is monitored every 3 to 6 months for 3 years as a marker of recurrence.

📷

CT Surveillance

Annual CT chest, abdomen and pelvis for 3 to 5 years to detect liver, lung or other metastases.

🔭

Colonoscopy

Colonoscopy at 1 year post-surgery, then every 3 to 5 years to detect metachronous polyps or tumours.

Do Not Delay, Early Detection Saves Lives

If you have symptoms that concern you, specialist assessment is essential.
Book a consultation with Mr. Lalit Kumar today.

Anatomy

Large Intestine

Quick Facts

UK incidence

42,000 cases/yr

Stage I survival

>90%

Stage III survival

~60%

Laparoscopic rate

>80%

Book a Consultation

Specialist opinion when it matters

Appointments typically within 3–5 working days.